Publications

Therapeutics in Ataxia

Soto, I., Bonomo, M., Nelthrope, B., Carr, B., Palmer, E., Sierra, M., Erturk, I., Peppercorn, D., Cox, E., Vasconcellos, T., Paulson, H., Shorrock, H., Srinivasan, S.R. "Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia Type 1 Via Rescue of Aberrant Splicing". (2026). Annals of Neurology 00:1-17. 

Srinivasan, S.R. “Targeting Circuit Abnormalities in Neurodegenerative Disorders”. (2023). Mol. Pharmacology 103(1):38-44.

Srinivasan, S.R., Huang, H., Chang, W-C., Strassmaier, T., and Shakkottai, V.G. “Discovery of novel activators of large-conductance calcium-activated potassium channels for the treatment of cerebellar ataxia.” (2022). Mol. Pharmacology 102(1):438-449.

Reviews and Book Chapters

Powers, R., Paulson, H., and Srinivasan, S.R.* “Trials for Cerebellar Ataxias: From Cellular Models to Human Therapies.” (2022) Contemporary Clinical Neuroscience (in press). *Corresponding author.

Srinivasan, S.R.; Melo de Gusmao, Claudio; Korecka, J.A.; Khurana, V. “Repeat Expansion Disorders”, Neurobiology of Disease (2022, in press).

Srinivasan, S.R. and Shakkottai, V.G. “Hereditary Ataxias” Hankey’s Neurology, 3rd Edition. (2020) ISBN-13: 978-0367280321.

Srinivasan, S.R. and Shakkottai, V.G. “Moving Towards Therapy in SCA1: Insights from Molecular Mechanisms, Identification of Novel Targets, and Planning for Human Trials.” (2019) Neurotherapeutics. (DOI 10.1007/s13311-019-00763-y).